Cohort studies1/26/2024 In doing so, we become one step closer towards achieving a more personalized healthcare approach. The data obtained from a variety of additional cohort studies has and continues to provide additional data that makes ToMMo’s biobank resources richer. The above additional cohort studies are only two, amongst many, cohort studies that ToMMo has implemented throughout the past decade. More details about joint research with OMRON Healthcare The results revealed that multiple measurements of the urinary sodium-to-potassium ratio demonstrated a more sensitive association with hypertension than single measurements. Using point-of-care testing devices distributed from OMRON Healthcare, participants were able to take multiple measurements of the sodium and potassium levels in their urine at various points in during their day. ToMMo and OMRON believe that one can create and maintain a healthy lifestyle from their own home. involves studying the urinary sodium-to-potassium ratio of participants. In doing so, ToMMo aims to provide information that can allow us to come up with ways to maintain a healthy brain and cognition throughout one’s lifetime.Īnother study implemented by ToMMo and OMRON Healthcare Co., Ltd. The purpose of this study is to better understand how the constitution of the brain and one’s lifestyle habits can affect the cognitive function of the brain. This study implements the use of MRI technology in studying different aspects of the human brain, in combination with cognitive psychology testing. The participants of the TMM CommCohort Study and TMM BirThree Cohort Study were asked to participate in further cohort studies, including but not limited to ‘The Brain-MRI Project’. Return of Genomic Results to Cohort Study Participants Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study).Community-Based Cohort Study (TMM CommCohort Study).Local residents who are 20 years old or older Detail of cohort studies Name of cohort study In doing so, ToMMo believes that this data can allow us to be closer towards the attainment of personalized healthcare, and thus, a healthier population with greater longevity. As the tertiary assessment brings the cohort studies to over the ten-year mark, ToMMo is interested in seeing the individual differences in health parameters that changes with age. The tertiary assessment resembles closely to that of the secondary assessment, however not only does it monitor the previous health parameters of interest, but additionally the participants’ memory/thinking abilities. Participants were requested to visit their closest community support center once every three to five years for biospecimen collection and subsequent analyses.Īs of July 2021, ToMMo has officially begun the tertiary assessment stage of the cohort studies. In order to grasp better understanding of the long term changes in health conditions, secondary and tertiary assessments were established as part of a follow-up study on participants whom undertook the baseline assessment. In the four years between the baseline and secondary assessments, participants were mailed an annual survey as part of the follow up of their health. The detailed health survey was conducted in the community support centers, located in seven locations across Miyagi Prefecture. This involved collection of biospecimens from the participants, including serum, plasma, mononuclear cells and urine along with conducting questionnaires regarding their lifestyle and medical history. To study how genetic factors and environmental factors affect disease risk, two large-scale prospective studies, the Tohoku Medical Megabank Project Community-Based Cohort Study (TMM CommCohort Study) and the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study), are ongoing in Miyagi and Iwate Prefectures in Japan.įrom 2013, the commencement of the cohort studies, till 2017, ToMMo has successfully recruited more than 150,000 participants to undertake the baseline assessment.
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